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文献信息
Development of combinative method using HPLC fingerprints and quantitative analysis for quality assessment of Chantaleela preparation
Abstract Chantaleela (CTL) is Thai traditional medicine composed of 8 medicinal herbs and borneol and used to treat fever. This study aimed to control the quality of CTL products by establishing a simple and comprehensive method using high performance liquid chromatography (HPLC). HPLC fingerprints of CTL were constructed for assessing qualitative parameters including identification and chemical profiling. This method was highly precise and accurate in quantifying the constituents of CTL’s markers including eurycomanone, loureirin A, imperatorin and atractylodin. The quality of the commercial CTL products in Thailand was assessed using this developed method. The chromatographic pattern was noticeably different from the established reference fingerprints. The substitution of Artemisia vulgaris for Artemisia annua was found in every commercial product. Moreover, the low content of marker compounds reflected the poor quality of the commercial products.
… 2.1 Reference standards Eurycomanone (95.79%), artemisinin (99.30%)
and loureirin A (99.43%) were purchased from Chengdu Biopurify
Phytochemicals (Chengdu, China). Apigenin (98.03%), imperatorin (99.27%) …
