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文献信息
Simplex lattice design for optimization of the mass ratio of Curcuma longa L., Curcuma zedoaria (Christm.) Roscoe and Curcuma aromatica Salisb. to maximize curcuminoids content and antioxidant activity
Curcuma longa L., Curcuma zedoaria (Christm.) Roscoe and Curcuma aromatica Salisb. are plants belonging to the Zingiberaceae family. The most extensively used parts of these three plants are the rhizomes. According to the Thai Herbal Pharmacopoeia (1), C. longa is used as stomachic, carminative, coloring agent and adstringent, whereas C. zedoaria is used as stomachic, antidiarrheal and emmenagogue. C. longa has several biological and pharmacological activities such as antioxidant, antiinflammatory, antiangiogenic and antiapoptotic (2). Additionally, it also exhibits antihyperlipidemic, anti-Alzheimer, antidepressant, antidiabetic, radioprotective and antimicrobial activities (3). C. aromatica exhibits antiinflammatory, wound healing, antitumor, anticancer, mosquito repellent, antiplatelet, antitussive, antioxidant, antimelanogenic and antinephrotoxic activities (4).
… EXPERIMENTAL Materials Three standard curcuminoids (purity ≥ 99%), ie., BDMC, DMC and CUR were pur- chased from Chengdu Biopurify Phytochemicals Ltd., China. DPPH (2,2-diphenyl-1-pic- rylhydrazyl) was purchased from Sigma-Aldrich Inc., USA …
