The design of infant formulas (IFs) seeks to resemble human milk (HM) composition and functionality. The fat sources used usually comprise vegetable oil blends to mimic the fatty acid composition of HM and introduce changes in the animal/plant sterol ratio. In contrast, the use of milk fat globule membrane (MFGM)-rich ingredients could improve this aspect by increasing the ratio. The present study evaluates the bioaccessibility (BA) of sterols (cholesterol, desmosterol, brassicasterol, campesterol, stigmasterol, and β-sitosterol) in three IFs (with or without MFGM) using an in vitro digestion method simulating infant conditions. Analytical parameters confirmed the suitability of the method for all of these sterols. Results showed the presence of MFGM to increase cholesterol content (6–7 vs 2 mg/100 mL), this being the most bioaccessible sterol in the IFs. Although the BA of cholesterol was reduced in MFGM-enriched IF (65.6–80.4% vs 99.7%), the intake of bioaccessible cholesterol from these IFs was higher.
… Campesterol (24α-methyl-5-cholesten-3β-ol, 99%) was purchased from Chengdu 125 Biopurify Phytochemicals Ltd. (Sichuan, China). Standard solutions of sterols were 126 …
Sterols in Infant Formulas: A Bioaccessibility Study
期刊名：Journal of Agricultural and Food Chemistry
文献编号：
文献地址： https://pubs.acs.org/doi/abs/10.1021/acs.jafc.7b04635
发表日期：January 25, 2018
文献编号：
文献地址： https://pubs.acs.org/doi/abs/10.1021/acs.jafc.7b04635
发表日期：January 25, 2018
