Vitex spp. have been reported as constituents of herbal preparations, namely Vitex peduncularis, commonly used in Asian countries. Unlike other species extensively investigated, reports on the biological activities and chemical profile of V. peduncularisare still scarce. In this work, the polyphenolic profile of V. peduncularis stem bark was unveiled, revealing a high content of apigenin and luteolin derivatives. More than 20 polyphenols were identified and quantitated for the first time, including C-rhamnosyl flavones infrequently reported. Regarding potential anti-inflammatory properties, the methanolic extract of the stem bark significantly reduced the levels of NO in macrophages, which may be a consequence of scavenging effect upon radical dot

NO. Significant inhibition of phospholipase A₂ activity was also noted. Consequently, the therapeutic applicability of this edible plant is also broadened due to the anti-inflammatory properties found.

... Louis, MO, US). 2.2. Phytochemical standards. Chlorogenic acid and 3,5-di-caffeoylquinic acid were obtained from Chengdu Biopurify Phytochemicals Ltd. (Sichuan, China). Vicenin-2 was from HWI Analytik GMBH (Rülzheim, Germany). ...

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专业生产定制高含量植提产品和中药成分

Anti-inflammatory properties of the stem bark from the herbal drug Vitex peduncularis Wall. ex Schauer and characterization of its polyphenolic profile

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