Effects of ginsenosides on rat jejunal contractility

Dapeng Chen, Yongjian Xiong, Chunling Jiang,Bochao Lv, Fangfei Liu, Li Wang & Yuan Lin

Abstract

Context: Ginsenosides are primary active ingredients of ginseng, which are believed to have various health benefits. It is found that the biotransformation of ginsenosides mainly takes place in the gastrointestinal tract and the information about ginsenosides-exerted effects on intestinal contractility is not sufficient.

Aims: The present study proposed that ginsenosides could exert stimulatory or inhibitory effects on intestinal motility depending on the assay condition-related intestinal contractile states and was to characterize the effects of ginsenosides on intestinal motility.

ginseng extract (Chengdu Biopurify Phytochemicals Ltd., China.